Kinetic spectrophotometric method for determination of amlodipine besylate in its pharmaceutical tablets
نویسندگان
چکیده
منابع مشابه
Kinetic spectrophotometric method for determination of amlodipine besylate in its pharmaceutical tablets
A simple and sensitive kinetic spectrophotometric method has been developed and validated for determination of amlodipine besylate (AML). The method was based on the condensation reaction of AML with 7-chloro-4-nitro-2,1,3-benzoxadiazole in an alkaline buffer (pH 8.6) producing a highly colored product. The color development was monitored spectrophometrically at the maximum absorption λmax 470 ...
متن کاملA Highly Sensitive Kinetic Spectrophotometric Method for the Determination of Ascorbic Acid in Pharmaceutical Samples
In this study, a new reaction system for quantitative determination of ascorbic acid was introduced. The developed method is based on inhibitory effect of ascorbic acid on the Orange G-bromate system. The change in absorbance was followed spectrophotometrically at 478 nm. The dependence of sensitivity on the reaction variables including reagents concentration, temperature and time was investiga...
متن کاملA Highly Sensitive Kinetic Spectrophotometric Method for the Determination of Ascorbic Acid in Pharmaceutical Samples
In this study, a new reaction system for quantitative determination of ascorbic acid was introduced. The developed method is based on inhibitory effect of ascorbic acid on the Orange G-bromate system. The change in absorbance was followed spectrophotometrically at 478 nm. The dependence of sensitivity on the reaction variables including reagents concentration, temperature and time was investiga...
متن کاملDerivative Spectrophotometric Method for Determination of Losartan in Pharmaceutical Formulations
Losartan, a highly effective blood pressure lowering agent, has been widely used for the treatment of hypertension. A fast and reliable method for the determination of losartan was highly desirable to support formulation screening and quality control. A first derivative UV spectroscopic method was developed for determination of losartan in the tablet dosage form. The first derivative spectrum r...
متن کاملKinetic Spectrophotometric Method for Determination of S032- Using Methylen blue
The present work reports a kinetic spectrophotometric method for the determination of traceamounts of sulphite that is based on inhibitory effect of sulphite on the oxidation of Methyleneblue (MB) in acidic media. The reaction is followed spectrophotometrically by monitoring thedecrease in absorbance of MB at 664 nm with a fixed time of 0.5-4.5 minutes. It was found thatsulphite exert a strong ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Pharmaceutical Analysis
سال: 2012
ISSN: 2095-1779
DOI: 10.1016/j.jpha.2012.03.002